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Revista científica ACS Publications: "Journal of Medical Chemistry"

Por Eddyson Jamir Flores Pérez (carné 2005).

Nuestro estudiantes recién graduados, también publican en revistas científicas internacionales. El artículo lleva por nombre: “Synthesis and Structure–Activity Analysis of New Phosphonium Salts with Potent Activity against African Trypanosomes”.

A series of 73 bisphosphonium salts and 10 monophosphonium salt derivatives were synthesized and tested in vitro against several wild type and resistant lines of Trypanosoma brucei (T. b. rhodesiense STIB900, T. b. brucei strain 427, TbAT1-KO, and TbB48). More than half of the compounds tested showed a submicromolar EC50 against these parasites.